The novel use of zinc chloride to catalyze the one-pot, three component synthesis of imidazo[1,2-a]pyridines from a range of substrates using either conventional heating or microwave irradiation is described. This methodology affords a number of imidazo[1,2-a]pyridines in reasonable yields and short reaction times without any significant optimization of the reaction conditions.
Rousseau, A. L., Matlaba, P., & Parkinson, C. J. (2007). Multicomponent synthesis of imidazo[1,2-a]pyridines using catalytic zinc chloride. Tetrahedron Letters, 48(23), 4079-4082. https://doi.org/10.1016/j.tetlet.2007.04.008