Multicomponent synthesis of imidazo[1,2-a]pyridines using catalytic zinc chloride

Amanda L. Rousseau, Pulane Matlaba, Christopher J. Parkinson

Research output: Contribution to journalArticle

128 Citations (Scopus)


The novel use of zinc chloride to catalyze the one-pot, three component synthesis of imidazo[1,2-a]pyridines from a range of substrates using either conventional heating or microwave irradiation is described. This methodology affords a number of imidazo[1,2-a]pyridines in reasonable yields and short reaction times without any significant optimization of the reaction conditions.
Original languageEnglish
Pages (from-to)4079-4082
Number of pages4
JournalTetrahedron Letters
Issue number23
Publication statusPublished - 04 Jun 2007

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