Palladium-catalysed arylation of sulfonamide stabilised enolates

Jacob G. Zeevaart, Christopher J. Parkinson, Charles B. De Koning

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

α-Arylation of methanesulfonamides using palladium catalysis is described. For example, treatment of N-benzyl-N-methylmethanesulfonamide with catalytic Pd(OAc)2 in the presence of sodium tert-butoxide, triphenylphosphine and toluene afforded N-benzyl-N- methylphenylmethanesulfonamide in 66% yield.

Original languageEnglish
Pages (from-to)1597-1599
Number of pages3
JournalTetrahedron Letters
Volume46
Issue number10
DOIs
Publication statusPublished - 07 Mar 2005

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