TY - JOUR
T1 - PCOS
T2 - an ovarian disorder that leads to dysregulation in the hypothalamic - pituitary - adrenal axis?
AU - Doi, Suhail AR
AU - Towers, Philip
AU - Scott, Christopher
AU - Al-Shoumer, Kamal AS
N1 - Imported on 12 Apr 2017 - DigiTool details were: Journal title (773t) = European Journal of Obstetrics Gynecology and Reproductive Biology. ISSNs: 0301-2115;
PY - 2005
Y1 - 2005
N2 - This review focuses on the role of the ovaries in the pathogenesis of the polycystic ovarian syndrome. In particular, the failure of follicular development, hypothalamo-pituitary dysregulation, alterations in adrenal steroid output and derangement of intermediary metabolism are discussed in the context of the ovaries. It is concluded that the central and adrenal alterations associated with PCOS are unlikely to be primary but rather are secondary to the events within the ovary.
AB - This review focuses on the role of the ovaries in the pathogenesis of the polycystic ovarian syndrome. In particular, the failure of follicular development, hypothalamo-pituitary dysregulation, alterations in adrenal steroid output and derangement of intermediary metabolism are discussed in the context of the ovaries. It is concluded that the central and adrenal alterations associated with PCOS are unlikely to be primary but rather are secondary to the events within the ovary.
U2 - 10.1016/j.ejogrb.2004.06.024
DO - 10.1016/j.ejogrb.2004.06.024
M3 - Article
SN - 0301-2115
VL - 118
SP - 4
EP - 16
JO - European Journal of Obstetrics and Gynecology and Reproductive Biology
JF - European Journal of Obstetrics and Gynecology and Reproductive Biology
IS - 1
ER -