Peri-operative acute kidney injury in dogs undergoing desexing surgery

Research output: Other contribution to conferenceAbstractpeer-review


Introduction: Acute kidney injury (AKI) is a potentially serious complication of anaesthesia and surgery. In dogs the incidence of peri-operative AKI is unknown.
Materials and Methods: Prospective cohort study of 165 (71 male and 94 female) dogs admitted for castration or ovariohysterectomy at a university teaching hospital (institutional animal care and ethics committee approval: A16025). Inclusion criteria were owners consent and no prior cardiac or renal disease. Blood samples were obtained prior to anaesthesia; and 24 and 48 hours post-operatively for measurement of serum creatinine (sCr). AKI was defined by an increase (>25 µmol l-1) in sCr from pre-operative to 24 or 48 hours post.
Results: Mean ± SD age and body weight were 2.1 ± 1.7 years and 20.3 ± 10 kg. Pre-operatively all dogs were euhydrated based on physical examination, pack cell volume and total plasma protein measurements. Pre-operative mean sCr was 103.2 ± 23.2 (reference range 44 – 150 µmol l-1). The mean change in pre sCr to 24 and 48 h was -3.8 ± 20.7 µmol l-1 and -3.8 ± 24.6 µmol l-1 respectively (p>0.05).
Creatinine increased > 25 µmol l-1 in four dogs at 24 hours and in an additional three dogs at 48 hours. Average increase for these dogs was 35.7 ± 31.1 µmol l-1 at 24 hours and 25.6 ± 5 µmol l-1 at 48 hours. In total seven dogs (4.3%) were classified as having AKI. One dog was grade 2 AKI (sCr 175 µmol l-1) and the other 6 were grade 1 (sCr increase > 25 µmol l-1 but within reference range). In addition, four dogs had overt oliguria in the first 24 hours post-op, including the dog with grade 2 AKI and two dogs with grade 1 AKI.
Conclusions: Peri-operative AKI may be a common complication of elective surgery in dogs.
Original languageEnglish
Number of pages1
Publication statusPublished - 29 Mar 2023
EventWorld Congress of Veterinary Anaesthesia and Analgesia 2023 - Sydney Masonic Centre, Sydney, Australia
Duration: 27 Mar 202330 Mar 2023
Conference number: 14 (Congress website) (Program) (Abstract program) (GP program) (Abstracts published in journal - unable to access volume)


ConferenceWorld Congress of Veterinary Anaesthesia and Analgesia 2023
OtherWe are excited to host the 2023 World Congress of Veterinary Anaesthesia & Analgesia (WCVAA) at the Sydney Masonic Centre in Sydney, Australia.

There is universal support within the Australian & New Zealand veterinary anaesthesia community to host the 2023 WCVAA and deliver an outstanding scientific program with a focus on Chronic Pain, as well as a 2-day pre-congress education program on acute pain and its management. We are putting together an excellent social program including a final afternoon at Sydney’s Taronga Zoo with an opportunity to see the world-famous Bird Show. WCVAA attendees and accompanying persons have every opportunity to participate in the social program and to sample Sydney’s friendly culture and nightlife all of which are on your doorstep.

Sydney is an easily accessible, vibrant, safe, friendly multi-national city and gateway to all that Australia has to offer. We can’t wait to welcome both our international and domestic visitors.

Whether before or after the WCVAA, Australia is ready to show you ‘the sights’ and the list is endless. On this website you’ll find suggestions of some locations and “How to Purchase Your International Airline Ticket” to cost effectively get here.
We look forward to hosting the 2023 WCVAA in Sydney.
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