PGRMC1 effects on metabolism, genomic mutation and CpG methylation imply crucial roles in animal biology and disease

Bashar M Thejer, Partho P Adhikary, Sarah L Teakel, Johnny Fang, Paul A Weston, Saliya Gurusinghe, Ayad G Anwer, Martin Gosnell, Jalal A Jazayeri, Marina Ludescher, Lesley-Ann Gray, Michael Pawlak, Robyn H Wallace, Sameer D Pant, Marie Wong, Tamas Fischer, Elizabeth J New, Tanja N Fehm, Hans Neubauer, Ewa M GoldysJane C Quinn, Leslie A Weston, Michael A Cahill

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Progesterone receptor membrane component 1 (PGRMC1) is often elevated in cancers, and exists in alternative states of phosphorylation. A motif centered on PGRMC1 Y180 was evolutionarily acquired concurrently with the embryological gastrulation organizer that orchestrates vertebrate tissue differentiation.
Original languageEnglish
Pages (from-to)26
JournalBMC Molecular and Cell Biology
Volume21
DOIs
Publication statusPublished - 15 Apr 2020

Fingerprint Dive into the research topics of 'PGRMC1 effects on metabolism, genomic mutation and CpG methylation imply crucial roles in animal biology and disease'. Together they form a unique fingerprint.

Cite this