Pharmacokinetics of single and multiple oral doses of meloxicam in foals less than 6 weeks of age.

Research output: Contribution to journalMeeting Abstract

Abstract

Selective COX-2 inhibitors target the cyclo-oxygenase iso-enzyme associated with pain and inflammation,rather than the constitutively expressed enzyme (COX-1) which is associated with protective or beneficial effects of prostaglandins. For this reason,it has been hypothesised that selective COX-2 inhibitors may be safer than non-selective nonsteroidal anti inflammatory drugs (NSAIDs). Meloxicam is a potent NSAID that has been shown to be an effective analgesic and anti-inflammatory in adult horses following oral administration. The current study reports preliminary findings from a pilot study to determine pharmacokinetics of meloxicam in foals less than 6 weeks of age.
Original languageEnglish
Pages (from-to)52-52
Number of pages1
JournalThe Australian Equine Veterinarian
Volume27
Issue number3
Publication statusPublished - 2008

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meloxicam
Cyclooxygenase 2 Inhibitors
Anti-Inflammatory Agents
Pharmacokinetics
Non-Steroidal Anti-Inflammatory Agents
Enzymes
Prostaglandin-Endoperoxide Synthases
Pharmaceutical Preparations
Horses
Prostaglandins
Oral Administration
Inflammation
Pain

Cite this

@article{e7716d7e97c34e95a24e5b83ad06210e,
title = "Pharmacokinetics of single and multiple oral doses of meloxicam in foals less than 6 weeks of age.",
abstract = "Selective COX-2 inhibitors target the cyclo-oxygenase iso-enzyme associated with pain and inflammation,rather than the constitutively expressed enzyme (COX-1) which is associated with protective or beneficial effects of prostaglandins. For this reason,it has been hypothesised that selective COX-2 inhibitors may be safer than non-selective nonsteroidal anti inflammatory drugs (NSAIDs). Meloxicam is a potent NSAID that has been shown to be an effective analgesic and anti-inflammatory in adult horses following oral administration. The current study reports preliminary findings from a pilot study to determine pharmacokinetics of meloxicam in foals less than 6 weeks of age.",
author = "Sharanne Raidal and Joe Pippia and Glenys Noble",
year = "2008",
language = "English",
volume = "27",
pages = "52--52",
journal = "The Australian Equine Veterinarian",
issn = "1032-6626",
number = "3",

}

Pharmacokinetics of single and multiple oral doses of meloxicam in foals less than 6 weeks of age. / Raidal, Sharanne; Pippia, Joe; Noble, Glenys.

In: The Australian Equine Veterinarian, Vol. 27, No. 3, 2008, p. 52-52.

Research output: Contribution to journalMeeting Abstract

TY - JOUR

T1 - Pharmacokinetics of single and multiple oral doses of meloxicam in foals less than 6 weeks of age.

AU - Raidal, Sharanne

AU - Pippia, Joe

AU - Noble, Glenys

PY - 2008

Y1 - 2008

N2 - Selective COX-2 inhibitors target the cyclo-oxygenase iso-enzyme associated with pain and inflammation,rather than the constitutively expressed enzyme (COX-1) which is associated with protective or beneficial effects of prostaglandins. For this reason,it has been hypothesised that selective COX-2 inhibitors may be safer than non-selective nonsteroidal anti inflammatory drugs (NSAIDs). Meloxicam is a potent NSAID that has been shown to be an effective analgesic and anti-inflammatory in adult horses following oral administration. The current study reports preliminary findings from a pilot study to determine pharmacokinetics of meloxicam in foals less than 6 weeks of age.

AB - Selective COX-2 inhibitors target the cyclo-oxygenase iso-enzyme associated with pain and inflammation,rather than the constitutively expressed enzyme (COX-1) which is associated with protective or beneficial effects of prostaglandins. For this reason,it has been hypothesised that selective COX-2 inhibitors may be safer than non-selective nonsteroidal anti inflammatory drugs (NSAIDs). Meloxicam is a potent NSAID that has been shown to be an effective analgesic and anti-inflammatory in adult horses following oral administration. The current study reports preliminary findings from a pilot study to determine pharmacokinetics of meloxicam in foals less than 6 weeks of age.

M3 - Meeting Abstract

VL - 27

SP - 52

EP - 52

JO - The Australian Equine Veterinarian

JF - The Australian Equine Veterinarian

SN - 1032-6626

IS - 3

ER -