Phytochemistry, ethnomedicine, and pharmacology of acacia

Nusrat Subhan, Geoffrey E. Burrows, Philip Kerr, Hassan K. Obied

Research output: Book chapter/Published conference paperChapter (peer-reviewed)

2 Citations (Scopus)

Abstract

Acacia sensu lato is a large and widespread genus of the family Fabaceae with more than 1350 species. Taxonomically, this genus is complex and has undergone substantial controversial revisions recently. Acacia have been used as folk medicines for the treatment of a wide range of disorders including gastrointestinal, respiratory, eye, skin, teeth, blood, uterine, and endocrine problems. Gums (heteropolysaccharides) and condensed tannins (flavan-3-ol derivatives) are the most commonly reported constituents in Acacia. Pharmacological studies, at least in vitro, have demonstrated antioxidant, analgesic, antihypertensive, antidiabetic, anti-Alzheimer's, and antimalarial effects of Acacia extracts. A number of secondary metabolites including phenols, alkaloids, and terpenoids, some with useful biological activities, have been reported in acacias. Very few species have been investigated for their phytochemical composition and biological activities. Hitherto, Acacia is largely an untapped resource of valuable secondary plant metabolites that have not gained enough scientific attention. This review aims to survey and critically appraise current literature on Acacia to provide sufficient baseline information for future work and potential commercial exploitation of Acacia.
Original languageEnglish
Title of host publicationStudies in natural products chemistry
Editors Atta-ur-Rahman
Place of PublicationAmsterdam, Netherlands
PublisherElsevier
Chapter9
Pages247-326
Number of pages80
Volume57
ISBN (Electronic)9780444640604
ISBN (Print)9780444640574
DOIs
Publication statusPublished - 19 Apr 2018

Publication series

NameStudies in Natural Products Chemistry
Volume57
ISSN (Print)1572-5995

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Subhan, N., Burrows, G. E., Kerr, P., & Obied, H. K. (2018). Phytochemistry, ethnomedicine, and pharmacology of acacia. In Atta-ur-Rahman (Ed.), Studies in natural products chemistry (Vol. 57, pp. 247-326). (Studies in Natural Products Chemistry; Vol. 57). Elsevier. https://doi.org/10.1016/B978-0-444-64057-4.00009-0