Acacia sensu lato is a large and widespread genus of the family Fabaceae with more than 1350 species. Taxonomically, this genus is complex and has undergone substantial controversial revisions recently. Acacia have been used as folk medicines for the treatment of a wide range of disorders including gastrointestinal, respiratory, eye, skin, teeth, blood, uterine, and endocrine problems. Gums (heteropolysaccharides) and condensed tannins (flavan-3-ol derivatives) are the most commonly reported constituents in Acacia. Pharmacological studies, at least in vitro, have demonstrated antioxidant, analgesic, antihypertensive, antidiabetic, anti-Alzheimer's, and antimalarial effects of Acacia extracts. A number of secondary metabolites including phenols, alkaloids, and terpenoids, some with useful biological activities, have been reported in acacias. Very few species have been investigated for their phytochemical composition and biological activities. Hitherto, Acacia is largely an untapped resource of valuable secondary plant metabolites that have not gained enough scientific attention. This review aims to survey and critically appraise current literature on Acacia to provide sufficient baseline information for future work and potential commercial exploitation of Acacia.
|Title of host publication||Studies in natural products chemistry|
|Place of Publication||Amsterdam, Netherlands|
|Number of pages||80|
|Publication status||Published - 19 Apr 2018|
|Name||Studies in Natural Products Chemistry|
Subhan, N., Burrows, G. E., Kerr, P., & Obied, H. K. (2018). Phytochemistry, ethnomedicine, and pharmacology of acacia. In Atta-ur-Rahman (Ed.), Studies in natural products chemistry (Vol. 57, pp. 247-326). (Studies in Natural Products Chemistry; Vol. 57). Elsevier. https://doi.org/10.1016/B978-0-444-64057-4.00009-0