Possible modes of action of the artemisinin-type compounds

Piero L. Olliaro; Richard K. Haynes; Bernard Meunier; Yongyuth Yuthavong

doi:10.1016/S1471-4922(00)01838-9

Possible modes of action of the artemisinin-type compounds

Piero L. Olliaro
, Richard K. Haynes
, Bernard Meunier
, Yongyuth Yuthavong

World Bank
Laboratoire De Chimie De Coordination Du CNRS
National Science and Technology Development Agency

Research output: Contribution to journal › Article › peer-review

214 Citations (Scopus)

Abstract

Artemisinin-type compounds are used for the treatment of uncomplicated and severe forms of malaria. They reduce parasitaemia more rapidly than any other antimalarial compound known, and are effective against multidrug-resistant parasites. However, uncertainties remain as to how they act on the parasite and cause toxicity. In this review, we summarize current ideas.

Original language	English
Pages (from-to)	122-126
Number of pages	5
Journal	Trends in Parasitology
Volume	17
Issue number	3
DOIs	https://doi.org/10.1016/S1471-4922(00)01838-9
Publication status	Published - 2001

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1016/S1471-4922(00)01838-9

Cite this

@article{04431819aed54dc584d72f711630d77f,

title = "Possible modes of action of the artemisinin-type compounds",

abstract = "Artemisinin-type compounds are used for the treatment of uncomplicated and severe forms of malaria. They reduce parasitaemia more rapidly than any other antimalarial compound known, and are effective against multidrug-resistant parasites. However, uncertainties remain as to how they act on the parasite and cause toxicity. In this review, we summarize current ideas.",

author = "Olliaro, \{Piero L.\} and Haynes, \{Richard K.\} and Bernard Meunier and Yongyuth Yuthavong",

year = "2001",

doi = "10.1016/S1471-4922(00)01838-9",

language = "English",

volume = "17",

pages = "122--126",

journal = "Trends in Parasitology",

issn = "1471-4922",

publisher = "Elsevier",

number = "3",

}

TY - JOUR

T1 - Possible modes of action of the artemisinin-type compounds

AU - Olliaro, Piero L.

AU - Haynes, Richard K.

AU - Meunier, Bernard

AU - Yuthavong, Yongyuth

PY - 2001

Y1 - 2001

N2 - Artemisinin-type compounds are used for the treatment of uncomplicated and severe forms of malaria. They reduce parasitaemia more rapidly than any other antimalarial compound known, and are effective against multidrug-resistant parasites. However, uncertainties remain as to how they act on the parasite and cause toxicity. In this review, we summarize current ideas.

AB - Artemisinin-type compounds are used for the treatment of uncomplicated and severe forms of malaria. They reduce parasitaemia more rapidly than any other antimalarial compound known, and are effective against multidrug-resistant parasites. However, uncertainties remain as to how they act on the parasite and cause toxicity. In this review, we summarize current ideas.

UR - https://www.scopus.com/pages/publications/0035005885

UR - https://www.scopus.com/pages/publications/0035005885#tab=citedBy

U2 - 10.1016/S1471-4922(00)01838-9

DO - 10.1016/S1471-4922(00)01838-9

M3 - Article

C2 - 11286794

AN - SCOPUS:0035005885

SN - 1471-4922

VL - 17

SP - 122

EP - 126

JO - Trends in Parasitology

JF - Trends in Parasitology

IS - 3

ER -

Possible modes of action of the artemisinin-type compounds

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this