Post-analytical issues in hemostasis and thrombosis testing

Emmanuel J Favaloro, Giuseppe Lippi

Research output: Book chapter/Published conference paperChapter (peer-reviewed)

5 Citations (Scopus)

Abstract

Analytical concerns within hemostasis and thrombosis testing are continuously decreasing. This is essentially attributable to modern instrumentation, improvements in test performance and reliability, as well as the application of appropriate internal quality control and external quality assurance measures. Pre-analytical issues are also being dealt with in some newer instrumentation, which are able to detect hemolysis, icteria and lipemia, and, in some cases, other issues related to sample collection such as tube under-filling. Post-analytical issues are generally related to appropriate reporting and interpretation of test results, and these are the focus of the current overview, which provides a brief description of these events, as well as guidance for their prevention or minimization. In particular, we propose several strategies for improved post-analytical reporting of hemostasis assays and advise that this may provide the final opportunity to prevent serious clinical errors in diagnosis.

Original languageEnglish
Title of host publicationHemostasis and thrombosis
Subtitle of host publicationMethods and protocols
Place of PublicationNew York
PublisherHumana Press
Chapter40
Pages545-559
Number of pages15
ISBN (Electronic)9781493971961
ISBN (Print) 9781493971947
DOIs
Publication statusPublished - 2017

Publication series

NameMethods in Molecular Biology
PublisherHumana Press
ISSN (Print)1064-3745

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