The coronavirus disease 2019 (COVID-19) pandemic has redefined the way nuclear medicine is practiced. The threat from COVID-19 to health and to the nuclear medicine community is rapidly changing. During the acute phase of COVID-19, there were significant direct and indirect impacts on nuclear medicine practice that have been previously detailed (1,2). It is useful to consider how COVID-19 will shape nuclear medicine practice as we reemerge from the acute phase (first wave) and prepare for both the second wave and practice after the COVID-19 crisis. With the impact and the government responses varying across the globe, there is some value in gleaning a global perspective. Here, a perspective from an Australian and New Zealand context is provided.