Preliminary results in the redox balance in healthy cats: Influence of age and gender

Cristina Castillo, Victor Pereira, Angel Abuelo, Rebeca Guimarey, Marco García-Vaquero, José L. Benedito, Joaquín Hernández

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Oxidative stress (OS) impairs organic function and is considered causally related to cellular senescence and death. This study aims to evaluate if the redox balance varies in relation to age and gender in healthy cats. To quantify the oxidative status of this species we determined the oxidative damage as serum reactive oxygen metabolites (ROM) and the total serum antioxidant capacity (SAC). In addition, we used the ratio of ROM to SAC as a measure of the oxidative balance, with higher values meaning higher oxidative stress (oxidative stress index). Our results suggest that the male population is at oxidative risk when compared with females, especially between the age of 2 and 7 years. Nutritional strategies in this population looking for additional antioxidant support would probably avoid the oxidative stress status that predisposes to chronic processes in senior male cats. Further clinical trials in this field are recommended.
Original languageEnglish
Pages (from-to)328-332
Number of pages5
JournalJournal of Feline Medicine and Surgery
Issue number4
Early online date2012
Publication statusPublished - 2013

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