Presumptive neural microsporidiosis in a young adult German Shepherd dog from rural Australia

Alice Birckhead, Martin Combs, Emma Croser, Alison Montgomery, Andrew Peters, Damien Stark, Richard Malik

Research output: Contribution to journalArticlepeer-review

Abstract

A 1‐year‐old, neutered male German Shepherd was presented with a 5‐month history of episodic lethargy, intermittent fever, weight loss and a hunched posture. The dog was diagnosed with presumptive microsporidian meningoencephalitis based on cytological findings on cerebrospinal fluid analysis and a positive PCR test. The dog initially responded favourably to a 4‐week course of trimethoprim‐sulfadiazine, pyrimethamine and fenbendazole, and remained well for 12 weeks following cessation of treatment. Disease then recurred, and despite an initial positive response to treatment, he deteriorated and was euthanased 11 weeks later, 7.5 months after definitive diagnosis and 13 months after clinical signs were first reported.
Original languageEnglish
Pages (from-to)351-355
Number of pages5
JournalAustralian Veterinary Journal
Volume99
Issue number8
Early online date26 Apr 2021
DOIs
Publication statusPublished - Aug 2021

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