Abstract
Peripheral arterial disease (PAD) affects 10'25% of people over the age of 55. It contributes to foot amputation, morbidity and mortality. Accurate and early diagnosis can lessen this public health burden. A current clinical measure of PAD such as the ankle brachial pressure index (ABPI) has low sensitivity and specificity for asymptomatic disease and calcified arteries especially in the diabetic population. Therefore, a new non-invasive evaluation method for lower limb vascularization has been investigated. Four groups of patients: non-diabetics and diabetics with and without foot problems and attending a diabetes complication screening clinic had their posterior tibial pulse velocity recorded. The pulse wave was segmented and inter-peak distances from 16-minute recordings identified. The tone-entropy algorithm for assessing pulse beat interval variation was applied to the data. Tone differentiated between non-diabetic and diabetes group with good foot health as well as for poor foot health. Entropy similarly was related to the level of foot health. A significant difference (p<0.05) was found between good foot health and poor foot health in the non-diabetes group. ABPI identified no significant differences between the four groups. The results suggest that the tone-entropy is a useful adjunct for screening for neuropathic-related foot problems that may be a risk indicator for peripheral arterial disease.
Original language | English |
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Title of host publication | IASTED 2011 |
Editors | C. Baumgartner |
Place of Publication | Calgary, Canada |
Publisher | ACTA Press |
Pages | 249-253 |
Number of pages | 5 |
ISBN (Electronic) | 9780889868663 |
DOIs | |
Publication status | Published - 2011 |
Event | The 8th IASTED International Conference on Biomedical Engineering - Grand Hotel Europa, Innsbruck, Austria Duration: 16 Feb 2011 → 18 Feb 2011 |
Conference
Conference | The 8th IASTED International Conference on Biomedical Engineering |
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Country/Territory | Austria |
City | Innsbruck |
Period | 16/02/11 → 18/02/11 |