Reduced Variability in Pulse Wave Velocity in Depressed Patients with Suicidal Ideation

Ahsan H Khandoker, Y Luthra, Y. Abouallaban, S Saha, R. Ahmed, R Mostafa, A.H. Chowdhury, Herbert Jelinek

Research output: Book chapter/Published conference paperConference paperpeer-review

8 Citations (Scopus)


Recently arterial stiffness was found to be associated with depression. The aim of this study was to investigate the association between arterial pulse wave velocity (PWV) and Major Depressive Disorder (MDD) with or without suicidal ideation. Twenty unmedicated MDD patients with a history of suicidal ideations (Age: 32.37±9.53 years) and 20 unmedicated MDD patients without any history of suicidal ideations (Age: 36.84±8.66) were recruited for this study at a psychiatric clinic in the UAE. Depression severity was assessed with the Hamilton Depression Rating Scale and the Beck Depression Inventory. Pulse wave velocity (PWV) was estimated from the ratio of half of the height and Pulse Transit Time which is defined as the time delay between the R-wave of the ECG and the arrival of the pulse wave in the index finger respectively. MDD Patients with suicidal ideation were found to have reduced low frequency (LF) and high frequency (HF) power of PWV compared to MDD patients without suicidal ideations. Suicidal score was negatively correlated (r=-0.54;p<0.05) with LF power and positively (r=0.54; p<0.01) with HF power. No difference in the average PWV was found between the two groups of participants. Reduced variability in pulse wave velocity in MDD patients with suicidal ideation may lead to arterial stiffness and higher risk of future cardiovascular disease.
Original languageEnglish
Title of host publicationComputing in Cardiology 2015
Subtitle of host publicationVolume 42
EditorsAlan Murray
Place of PublicationUnited States
PublisherIEEE, Institute of Electrical and Electronics Engineers
Number of pages4
ISBN (Electronic)9781509006847
ISBN (Print)9781509006854
Publication statusPublished - 2015
Event42nd Computing in Cardiology Conference, CinC 2015
- Saint Jean d’Angely Campus, University of Nice, Nice, France
Duration: 06 Sept 201509 Sept 2015 (Conference proceedings) (Conference website)

Publication series

ISSN (Print)2325-8861


Conference42nd Computing in Cardiology Conference, CinC 2015
OtherComputing in Cardiology provides an international forum for scientists and professionals from the fields of medicine, physics, engineering and computer science, and has been held annually since 1974.
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