Relationship between pericardial fluid B-type natriuretic peptide and ventricular structure and function.

Li-ping Chen, Tie-Min Wei, Lexin Wang

Research output: Contribution to journalArticle

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Abstract

The pericardial fluid BNP and plasma BNP concentrations were measured in 18 patients underwent surgical repair of ventricular septal defect (VSD). The levels of BNP in the pericardial fluid (324.8 ± 137.3 pg/ml) were higher than that in the plasma (20.75 ± 6.05 pg/ml) (P=0.034). Pericardial fluid BNP was correlated with the plasma BNP (r=0.85, p<0.01). A good correlation was also found between the pericardial fluid BNP levels and left atrial diameter, left ventricular end-diastolic and end-systolic diameter, left ventricular ejection fraction, right ventricular diameter and mean pulmonary artery pressure (p<0.05). We conclude that the levels of BNP in pericardial fluid were higher than that in the plasma. Similar to plasma BNP, pericardial fluid BNP is also related to the ventricular diameter and function.
Original languageEnglish
Pages (from-to)326-329
Number of pages4
JournalArchives of Medical Research
Volume38
Issue number3
DOIs
Publication statusPublished - 2007

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