TY - JOUR
T1 - Restless legs syndrome
AU - Nanayakkara, Budhima
AU - Di Michiel, James
AU - Yee, Brendon J.
N1 - Publisher Copyright:
© The Royal Australian College of General Practitioners 2023
PY - 2023/9/1
Y1 - 2023/9/1
N2 - BACKGROUND: Restless legs syndrome (RLS) is a common sensorimotor disorder causing significant distress and is commonly seen in the primary care setting. OBJECTIVE: This article outlines the epidemiology, pathophysiology, diagnosis and management of RLS, with a focus on the primary care setting. DISCUSSION: RLS is a clinical diagnosis, although mimics exist. Brain iron deficiency, dopaminergic dysfunction and genetics underpin the poorly understood pathophysiology of this common condition. After repleting iron stores, reviewing any exacerbating medications and attending to non-pharmacological management options, there are pharmacological options that prove to be effective, although with class-specific effects that need to be considered.
AB - BACKGROUND: Restless legs syndrome (RLS) is a common sensorimotor disorder causing significant distress and is commonly seen in the primary care setting. OBJECTIVE: This article outlines the epidemiology, pathophysiology, diagnosis and management of RLS, with a focus on the primary care setting. DISCUSSION: RLS is a clinical diagnosis, although mimics exist. Brain iron deficiency, dopaminergic dysfunction and genetics underpin the poorly understood pathophysiology of this common condition. After repleting iron stores, reviewing any exacerbating medications and attending to non-pharmacological management options, there are pharmacological options that prove to be effective, although with class-specific effects that need to be considered.
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U2 - 10.31128/AJGP-02-23-6722
DO - 10.31128/AJGP-02-23-6722
M3 - Article
C2 - 37666782
AN - SCOPUS:85169848447
SN - 2208-7958
VL - 52
SP - 615
EP - 621
JO - Australian Journal of General Practice
JF - Australian Journal of General Practice
IS - 9
ER -