Rice bran derived bioactive compounds modulate risk factors of cardiovascular disease and type 2 diabetes mellitus: An updated review

Research output: Contribution to journalReview article

Abstract

Cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM) are two chronic diseases that have claimed more lives globally than any other disease. Dietary supplementation of functional foods containing bioactive compounds is recognised to result in improvements in free-radical-mediated oxidative stress. Emerging evidence indicates that bioactive compounds derived from rice bran (RB) have therapeutic potential against cellular oxidative stress. This review aims to describe the mechanistic pathways behind CVD and T2DM development and the therapeutic potential of polyphenols derived from RB against these chronic diseases.

Original languageEnglish
Article number2736
Pages (from-to)1-36
Number of pages36
JournalNutrients
Volume11
Issue number11
DOIs
Publication statusPublished - 12 Nov 2019

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rice bran
chronic diseases
noninsulin-dependent diabetes mellitus
Type 2 Diabetes Mellitus
cardiovascular diseases
Oxidative Stress
Chronic Disease
oxidative stress
Cardiovascular Diseases
risk factors
therapeutics
Functional Food
Polyphenols
Dietary Supplements
functional foods
Free Radicals
dietary supplements
polyphenols
Therapeutics
bioactive compounds

Cite this

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title = "Rice bran derived bioactive compounds modulate risk factors of cardiovascular disease and type 2 diabetes mellitus: An updated review",
abstract = "Cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM) are two chronic diseases that have claimed more lives globally than any other disease. Dietary supplementation of functional foods containing bioactive compounds is recognised to result in improvements in free-radical-mediated oxidative stress. Emerging evidence indicates that bioactive compounds derived from rice bran (RB) have therapeutic potential against cellular oxidative stress. This review aims to describe the mechanistic pathways behind CVD and T2DM development and the therapeutic potential of polyphenols derived from RB against these chronic diseases.",
keywords = "Bioactive compounds, Cardiovascular disease, Rice bran, Type 2 diabetes mellitus",
author = "Nancy Saji and Nidhish Francis and Schwarz, {Lachlan J.} and Blanchard, {Christopher L.} and Santhakumar, {Abishek B.}",
year = "2019",
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T1 - Rice bran derived bioactive compounds modulate risk factors of cardiovascular disease and type 2 diabetes mellitus

T2 - An updated review

AU - Saji, Nancy

AU - Francis, Nidhish

AU - Schwarz, Lachlan J.

AU - Blanchard, Christopher L.

AU - Santhakumar, Abishek B.

PY - 2019/11/12

Y1 - 2019/11/12

N2 - Cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM) are two chronic diseases that have claimed more lives globally than any other disease. Dietary supplementation of functional foods containing bioactive compounds is recognised to result in improvements in free-radical-mediated oxidative stress. Emerging evidence indicates that bioactive compounds derived from rice bran (RB) have therapeutic potential against cellular oxidative stress. This review aims to describe the mechanistic pathways behind CVD and T2DM development and the therapeutic potential of polyphenols derived from RB against these chronic diseases.

AB - Cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM) are two chronic diseases that have claimed more lives globally than any other disease. Dietary supplementation of functional foods containing bioactive compounds is recognised to result in improvements in free-radical-mediated oxidative stress. Emerging evidence indicates that bioactive compounds derived from rice bran (RB) have therapeutic potential against cellular oxidative stress. This review aims to describe the mechanistic pathways behind CVD and T2DM development and the therapeutic potential of polyphenols derived from RB against these chronic diseases.

KW - Bioactive compounds

KW - Cardiovascular disease

KW - Rice bran

KW - Type 2 diabetes mellitus

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