Rice bran derived bioactive compounds modulate risk factors of cardiovascular disease and type 2 diabetes mellitus: An updated review

Nancy Saji; Nidhish Francis; Lachlan J. Schwarz; Christopher L. Blanchard; Abishek B. Santhakumar

doi:10.3390/nu11112736

Rice bran derived bioactive compounds modulate risk factors of cardiovascular disease and type 2 diabetes mellitus: An updated review

Nancy Saji
, Nidhish Francis
, Lachlan J. Schwarz
, Christopher L. Blanchard
, Abishek B. Santhakumar

Research output: Contribution to journal › Review article › peer-review

36 Citations (Scopus)

95 Downloads (Pure)

Abstract

Cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM) are two chronic diseases that have claimed more lives globally than any other disease. Dietary supplementation of functional foods containing bioactive compounds is recognised to result in improvements in free-radical-mediated oxidative stress. Emerging evidence indicates that bioactive compounds derived from rice bran (RB) have therapeutic potential against cellular oxidative stress. This review aims to describe the mechanistic pathways behind CVD and T2DM development and the therapeutic potential of polyphenols derived from RB against these chronic diseases.

Original language	English
Article number	2736
Number of pages	36
Journal	Nutrients
Volume	11
Issue number	11
DOIs	https://doi.org/10.3390/nu11112736
Publication status	Published - 12 Nov 2019

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SDG 3 Good Health and Well-being

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10.3390/nu11112736

34809603 published articleFinal published version, 330 KB

Cite this

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title = "Rice bran derived bioactive compounds modulate risk factors of cardiovascular disease and type 2 diabetes mellitus: An updated review",

abstract = "Cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM) are two chronic diseases that have claimed more lives globally than any other disease. Dietary supplementation of functional foods containing bioactive compounds is recognised to result in improvements in free-radical-mediated oxidative stress. Emerging evidence indicates that bioactive compounds derived from rice bran (RB) have therapeutic potential against cellular oxidative stress. This review aims to describe the mechanistic pathways behind CVD and T2DM development and the therapeutic potential of polyphenols derived from RB against these chronic diseases.",

keywords = "Bioactive compounds, Cardiovascular disease, Rice bran, Type 2 diabetes mellitus",

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T2 - An updated review

AU - Saji, Nancy

AU - Francis, Nidhish

AU - Schwarz, Lachlan J.

AU - Blanchard, Christopher L.

AU - Santhakumar, Abishek B.

PY - 2019/11/12

Y1 - 2019/11/12

N2 - Cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM) are two chronic diseases that have claimed more lives globally than any other disease. Dietary supplementation of functional foods containing bioactive compounds is recognised to result in improvements in free-radical-mediated oxidative stress. Emerging evidence indicates that bioactive compounds derived from rice bran (RB) have therapeutic potential against cellular oxidative stress. This review aims to describe the mechanistic pathways behind CVD and T2DM development and the therapeutic potential of polyphenols derived from RB against these chronic diseases.

AB - Cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM) are two chronic diseases that have claimed more lives globally than any other disease. Dietary supplementation of functional foods containing bioactive compounds is recognised to result in improvements in free-radical-mediated oxidative stress. Emerging evidence indicates that bioactive compounds derived from rice bran (RB) have therapeutic potential against cellular oxidative stress. This review aims to describe the mechanistic pathways behind CVD and T2DM development and the therapeutic potential of polyphenols derived from RB against these chronic diseases.

KW - Bioactive compounds

KW - Cardiovascular disease

KW - Rice bran

KW - Type 2 diabetes mellitus

UR - https://www.scopus.com/pages/publications/85074924151

UR - https://www.scopus.com/pages/publications/85074924151#tab=citedBy

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M3 - Review article

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AN - SCOPUS:85074924151

SN - 2072-6643

VL - 11

JO - Nutrients

JF - Nutrients

IS - 11

M1 - 2736

ER -

Rice bran derived bioactive compounds modulate risk factors of cardiovascular disease and type 2 diabetes mellitus: An updated review

Abstract

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