@article{fa75adc61b65400da32eea5cc34fc88b,
title = "Road to the elimination of schistosomiasis from Asia: The journey is far from over",
abstract = "Schistosomiasis is a neglected tropical disease with a very long endemic history in Asia. Great strides have been made to control the disease in China and the Philippines but the road to elimination is far from over, given the zoonotic nature of the schistosome parasites in both countries.",
keywords = "Asia, Control, Elimination, Neglected tropical disease, Schistosomiasis",
author = "Ross, {Allen G.P.} and Olveda, {Remigio M.} and Luz Acosta and Harn, {Donald A.} and Delia Chy and Yuesheng Li and Gray, {Darren J.} and Gordon, {Catherine A.} and McManus, {Donald P.} and Williams, {Gail M.}",
note = "Funding Information: The authors would like to thank the UBS-Optimus Foundation , the National Health and Medical Research Council , Australia for providing financial support for the schistosomiasis research in the Philippines, and the National Institutes of Health Award (A1068109) to DAH (USA) for support of production of the schistosome vaccines. YSL is an Australian Research Council Future fellow; DJG is an Australian Research Council fellow (DECRA); DPM is an NHMRC Senior Principal Research Fellow. Funding Information: Schistosomiasis was first reported in 1906 in the Philippines and there are approximately 865,000 people infected and another seven million at risk of infection [3] . Major endemic foci are in the poorest regions of the Visayas (Samar and Leyte) and Mindanao ( Fig. 2 ) [7–9] . This includes 24 provinces, 183 municipalities and 1212 barangays (villages) [8] . In 2003 new endemic areas were identified in the northern part of the Philippines. The national schistosomiasis control program was established in 1961 and comprised of passive surveillance and mass praziquantel (PZQ) chemotherapy [8,9] . Unfortunately, control has been sporadic and complicated due to inadequate funding and the zoonotic nature of schistosomiasis japonica. In 1991 the Philippine Health Development Project (PHDP), funded by the World Bank, was initiated for communicable disease control, including schistosomiasis. The PHPD was an intensive case finding and PZQ chemotherapy-based program aimed at treating all infected individuals and was, at first successful in lowering the prevalence of schistosomiasis in the Philippines. However, like similar control programs in Africa and China, following the termination of the PHPD in 1995, schistosome prevalence rebounded due to the inability of PZQ to prevent re-infection and the return to sporadic control [10] . ",
year = "2013",
month = nov,
doi = "10.1016/j.micinf.2013.07.010",
language = "English",
volume = "15",
pages = "858--865",
journal = "Microbes and Infection",
issn = "1286-4579",
publisher = "Elsevier Masson s.r.l.",
number = "13",
}
