Sequence comparison of pigeon circoviruses.

D. Todd, E. Fringuelli, A.N.J. Scott, B.J. Borghmans, J.P. Duchatel, H.L. Shivaprasad, Shane Raidal, J.X. Abadie, M.P. Francisioni, J.A. Smyth

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25 Citations (Scopus)


The genome sequences of eight pigeon circoviruses (PiCV) were determined and compared with four previously published sequences. The viruses compared were from the USA, five European countries, China and Australia and included PiCVs from racing, feral, ornamental and meat pigeons and a Senegal dove (Streptopelia senegalensis). The 12 PiCV genomes, ranging from 2032 to 2040 nucleotides in length, displayed similar organizations. Pairwise comparisons showed that the genome nucleotide sequence identities ranged from 85.1% to 97.8% and that the amino acid identities of the putative replication associated (Rep) and putative capsid (Cap) proteins displayed ranges of 91.5'99.1% and 73.0'99.3%, respectively. Comparative analyses identified conserved nucleotide sequences within the Rep gene and 3' intergenic regions, which would be suitable for diagnostic PCR primers, and variable amino acid sequences within the capsid proteins, which should be considered when selecting virus isolates for vaccine development.
Original languageEnglish
Pages (from-to)311-319
Number of pages9
JournalResearch in Veterinary Science
Issue number2
Publication statusPublished - 2008

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    Todd, D., Fringuelli, E., Scott, A. N. J., Borghmans, B. J., Duchatel, J. P., Shivaprasad, H. L., Raidal, S., Abadie, J. X., Francisioni, M. P., & Smyth, J. A. (2008). Sequence comparison of pigeon circoviruses. Research in Veterinary Science, 84(2), 311-319.