Seroprevalence of Trypanosoma cruzi in blood donors at the National Blood Transfusion Services: Guyana

Phillip Bwititi, Paprica Browne

Research output: Contribution to journalArticle

2 Citations (Scopus)
14 Downloads (Pure)

Abstract

Introduction: Blood transfusion is an important transmission route of Trypanosoma cruzi (T cruzi), a major parasitic infection in Central and South America. The limited treatment options are most effective in acute Chagas' infection. At present, there is no current data on the prevalence of T cruzi in the blood donor population of Guyana. This information is necessary to protect the supply of the blood donation programme. This study sought to determine the prevalence of T cruzi in the blood supply at the National Blood Transfusion Services of Guyana with the hope of providing knowledge to the on-going surveillance for Chagas' disease worldwide and therefore address the risk of its spread by blood transfusion. Methods: Two commercialized ELISAs utilizing crude or recombinant T cruzi antigens were used to study 2000 blood samples voluntarily donated for the purpose of altruistic or family replacement donation retrospectively.
Original languageEnglish
Pages (from-to)559-563
Number of pages5
JournalWest Indian Medical Journal
Volume61
Issue number6
Publication statusPublished - Sep 2012

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