Simple quantitative planimetric measurement of nigrosome-1 for the diagnosis of Parkinson's disease in clinical settings

Minh (Shayne) Chau, Marc Agzarian, Robert A Wilcox, Andrew Dwyer, Eva Bezak, Gabrielle Todd

Research output: Other contribution to conferenceAbstractpeer-review


There is currently no definitive diagnostic test for Parkinson’s disease. A hypointense appearance of nigrosome-1 on MRI has been proposed as a biomarker for Parkinson’s disease. Current clinical practice involves a subjectively rating the appearance of nigrosome-1 on susceptibility-weighted images.1 The aim of the current study was to develop and test a simple method for quantifying nigrosome-1 in clinical settings. We hypothesised that area of nigrosome-1 hyperintense signal exhibits higher inter-rater reliability than subjective rating of nigrosome-1 appearance.
Original languageEnglish
Number of pages1
Publication statusPublished - 2023
EventASMIRT 2023 Conference - International Convention Centre, Sydney, Australia
Duration: 27 Apr 202330 Apr 2023 (Program) (Abstracts)


ConferenceASMIRT 2023 Conference
Abbreviated titleChampions of change. Honouring the past, embracing the present, shaping the future
OtherThe theme for this year’s Conference is Champions of change – Honouring the past | Embracing the present | Shaping the future.

We are looking for you, our current and future champions, to submit workshop proposals and abstracts. The conference will comprise an engaging program including a mixture of invited speakers, proffered papers, vibrant physical posters, specialised workshops and so much more.

Honour the past by sharing previous learnings and knowledge and how they still relate to current practice
Embrace the present by networking, collaborating and reconnecting with your peers and others in the profession
Shape the future by sharing your latest research and workplace protocols, professional standards and ongoing improvement of practice and person centred care across our profession.
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