Statins and coronary artery disease

Fiona White, Lexin Wang

Research output: Contribution to journalArticlepeer-review


Statins have been proven to be clinically effective in both the prevention and treatment of coronary artery disease. Coronary artery disease is a common and serious condition due to an underlying pathology of atherosclerosis, which is caused mainly by increased levels of low-density lipoprotein that accumulate in the walls of the coronary arteries. The main treatment option for high cholesterol levels is a group of cholesterol-lowering drugs called statins. They act mainly on the liver enzymes responsible for cholesterol synthesis, reducing the production of cholesterol. This has been proven to be very effective in decreasing the morbidity and mortality associated with coronary artery disease, as evidenced in a number of clinical trials and studies using statins.
Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalInternet Journal of Cardiovascular Research
Issue number1
Publication statusPublished - 2006


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