Stereocontrolled synthesis of calyculin A: Construction of the C(1)-C(14) tetraene nitrile unit

Anthony G M Barrett; Jeremy J. Edmunds; James A. Hendrix; Kiyoshi Horita; Christopher J. Parkinson

doi:10.1039/C39920001238

Stereocontrolled synthesis of calyculin A: Construction of the C(1)-C(14) tetraene nitrile unit

Anthony G M Barrett
, Jeremy J. Edmunds
, James A. Hendrix
, Kiyoshi Horita
, Christopher J. Parkinson

Dentistry and Medical Sciences

Colorado State University
Northwestern University

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Abstract

An enantioselective and geometrically selective synthesis of the C(1)-C(14) tetraene nitrile unit of calyculin A, using aldol chemistry with (+)-(E)-diisopinocampheylborane and Stille coupling, is described.

Original language	English
Pages (from-to)	1238-1240
Number of pages	3
Journal	Journal of the Chemical Society, Chemical Communications
Issue number	17
DOIs	https://doi.org/10.1039/C39920001238
Publication status	Published - 1992

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title = "Stereocontrolled synthesis of calyculin A: Construction of the C(1)-C(14) tetraene nitrile unit",

abstract = "An enantioselective and geometrically selective synthesis of the C(1)-C(14) tetraene nitrile unit of calyculin A, using aldol chemistry with (+)-(E)-diisopinocampheylborane and Stille coupling, is described.",

author = "Barrett, \{Anthony G M\} and Edmunds, \{Jeremy J.\} and Hendrix, \{James A.\} and Kiyoshi Horita and Parkinson, \{Christopher J.\}",

year = "1992",

doi = "10.1039/C39920001238",

language = "English",

pages = "1238--1240",

journal = "Journal of the Chemical Society, Chemical Communications",

issn = "0022-4936",

publisher = "Royal Society of Chemistry",

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T1 - Stereocontrolled synthesis of calyculin A

T2 - Construction of the C(1)-C(14) tetraene nitrile unit

AU - Barrett, Anthony G M

AU - Edmunds, Jeremy J.

AU - Hendrix, James A.

AU - Horita, Kiyoshi

AU - Parkinson, Christopher J.

PY - 1992

Y1 - 1992

N2 - An enantioselective and geometrically selective synthesis of the C(1)-C(14) tetraene nitrile unit of calyculin A, using aldol chemistry with (+)-(E)-diisopinocampheylborane and Stille coupling, is described.

AB - An enantioselective and geometrically selective synthesis of the C(1)-C(14) tetraene nitrile unit of calyculin A, using aldol chemistry with (+)-(E)-diisopinocampheylborane and Stille coupling, is described.

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UR - https://www.scopus.com/pages/publications/0026799471#tab=citedBy

U2 - 10.1039/C39920001238

DO - 10.1039/C39920001238

M3 - Article

AN - SCOPUS:0026799471

SN - 0022-4936

SP - 1238

EP - 1240

JO - Journal of the Chemical Society, Chemical Communications

JF - Journal of the Chemical Society, Chemical Communications

IS - 17

ER -

Stereocontrolled synthesis of calyculin A: Construction of the C(1)-C(14) tetraene nitrile unit

Abstract

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