Synthesis and biophysical analysis of Naringin-Chitooligosaccharide complex

Ruge Cao, Xueyang Li, Zhongkai Zhou, Zhenyu Zhao

Research output: Contribution to journalArticle

4 Citations (Scopus)


In this study, new complexes of Naringin and Chitooligosaccharide (Nari-COS) at different mole ratios (1:1, 1:5, 1:10) were prepared by spray-drying method so as to enhance the water solubility and weaken the bitterness of naringin. At the same time, the antioxidant and the antibacterial properties of this complex were evaluated. SEM, FTIR, 1H NMR analysis confirmed the successful synthesis of Nari-COS formed through hydrogen bonds between the A, B rings of naringin and COS. Nari-COS exhibited significantly better water solubility, reduced bitterness, stronger antioxidant capacity, and enhanced antibacterial property in comparison to pure naringin, benefitting the extensive application of natural products in foods.

Original languageEnglish
Pages (from-to)1-8
Number of pages8
JournalNatural Product Research
Publication statusE-pub ahead of print - 13 Jun 2019

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