Synthesis and biophysical analysis of Naringin-Chitooligosaccharide complex

Ruge Cao, Xueyang Li, Zhongkai Zhou, Zhenyu Zhao

    Research output: Contribution to journalArticlepeer-review

    13 Citations (Scopus)


    In this study, new complexes of Naringin and Chitooligosaccharide (Nari-COS) at different mole ratios (1:1, 1:5, 1:10) were prepared by spray-drying method so as to enhance the water solubility and weaken the bitterness of naringin. At the same time, the antioxidant and the antibacterial properties of this complex were evaluated. SEM, FTIR, 1H NMR analysis confirmed the successful synthesis of Nari-COS formed through hydrogen bonds between the A, B rings of naringin and COS. Nari-COS exhibited significantly better water solubility, reduced bitterness, stronger antioxidant capacity, and enhanced antibacterial property in comparison to pure naringin, benefitting the extensive application of natural products in foods.

    Original languageEnglish
    Pages (from-to)305-311
    Number of pages8
    JournalNatural Product Research
    Issue number2
    Early online date13 Jun 2019
    Publication statusPublished - 2021


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