Synthesis and Evaluation of a Molecularly Imprinted Polymer Selective to 2,4,6-Trichloroanisole

Lachlan Schwarz, Michael Bowyer, I. Holdsworth Dr Clovia, Adam McCluskey

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


In the wine industry 2,4,6-trichloroanisole (TCA) has been identified as the primary contaminant responsible for 'cork taint'. A molecularly imprinted polymer (MIP) selective for TCA was prepared in three porogens (hexane, acetonitrile, and dichloromethane) of varying polarities using non-covalent molecular imprinting techniques. Target rebinding to the MIP was found to be most effective in its porogenic solvent and highest in dichloromethane (imprinting factor = 3.65). Competitive binding assays performed against a range of close structural analogues demonstrated a preference for the target molecule.
Original languageEnglish
Pages (from-to)759-764
Number of pages6
JournalAustralian Journal of Chemistry
Publication statusPublished - 2006


Dive into the research topics of 'Synthesis and Evaluation of a Molecularly Imprinted Polymer Selective to 2,4,6-Trichloroanisole'. Together they form a unique fingerprint.

Cite this