Systematic evaluation of exposure to trace elements and minerals in patients with chronic kidney disease of uncertain etiology (CKDu) in Sri Lanka

Shanika Nanayakkara; Lala Senevirathna; Kouji H Harada; Rohana Chandrajith; Toshiaki Hitomi; Tilak Abeysekera; Eri Muso; Takao Watanabe; Akio Koizumi

doi:10.1016/j.jtemb.2019.04.019

Systematic evaluation of exposure to trace elements and minerals in patients with chronic kidney disease of uncertain etiology (CKDu) in Sri Lanka

Shanika Nanayakkara, Lala Senevirathna, Kouji H Harada, Rohana Chandrajith, Toshiaki Hitomi, Tilak Abeysekera, Eri Muso, Takao Watanabe, Akio Koizumi

Research output: Contribution to journal › Article › peer-review

42 Citations (Scopus)

Abstract

Chronic kidney disease of uncertain etiology (CKDu) in areas in and around Sri Lanka’s North Central Province has been identified as a major non-communicable disease due to its high prevalence and the burden on the public health system. Controversial evidence relating to the etiology and risk factors of CKDu has been reported. The most debated is the role of trace elements such as Cd and As in the pathogenesis of CKDu.

Original language	English
Pages (from-to)	206-213
Number of pages	8
Journal	Journal of Trace Elements in Medicine and Biology
Volume	54
DOIs	https://doi.org/10.1016/j.jtemb.2019.04.019
Publication status	Published - Jul 2019

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Nanayakkara, S., Senevirathna, L., Harada, K. H., Chandrajith, R., Hitomi, T., Abeysekera, T., Muso, E., Watanabe, T., & Koizumi, A. (2019). Systematic evaluation of exposure to trace elements and minerals in patients with chronic kidney disease of uncertain etiology (CKDu) in Sri Lanka. Journal of Trace Elements in Medicine and Biology, 54, 206-213. https://doi.org/10.1016/j.jtemb.2019.04.019

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abstract = "Chronic kidney disease of uncertain etiology (CKDu) in areas in and around Sri Lanka{\textquoteright}s North Central Province has been identified as a major non-communicable disease due to its high prevalence and the burden on the public health system. Controversial evidence relating to the etiology and risk factors of CKDu has been reported. The most debated is the role of trace elements such as Cd and As in the pathogenesis of CKDu.",

keywords = "Chronic kidney disease, Sri Lanka, Cadmium, Arsenic, Trace elements, Minerals",

author = "Shanika Nanayakkara and Lala Senevirathna and Harada, {Kouji H} and Rohana Chandrajith and Toshiaki Hitomi and Tilak Abeysekera and Eri Muso and Takao Watanabe and Akio Koizumi",

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doi = "10.1016/j.jtemb.2019.04.019",

language = "English",

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Nanayakkara, S, Senevirathna, L, Harada, KH, Chandrajith, R, Hitomi, T, Abeysekera, T, Muso, E, Watanabe, T & Koizumi, A 2019, 'Systematic evaluation of exposure to trace elements and minerals in patients with chronic kidney disease of uncertain etiology (CKDu) in Sri Lanka', Journal of Trace Elements in Medicine and Biology, vol. 54, pp. 206-213. https://doi.org/10.1016/j.jtemb.2019.04.019

TY - JOUR

T1 - Systematic evaluation of exposure to trace elements and minerals in patients with chronic kidney disease of uncertain etiology (CKDu) in Sri Lanka

AU - Nanayakkara, Shanika

AU - Senevirathna, Lala

AU - Harada, Kouji H

AU - Chandrajith, Rohana

AU - Hitomi, Toshiaki

AU - Abeysekera, Tilak

AU - Muso, Eri

AU - Watanabe, Takao

AU - Koizumi, Akio

PY - 2019/7

Y1 - 2019/7

N2 - Chronic kidney disease of uncertain etiology (CKDu) in areas in and around Sri Lanka’s North Central Province has been identified as a major non-communicable disease due to its high prevalence and the burden on the public health system. Controversial evidence relating to the etiology and risk factors of CKDu has been reported. The most debated is the role of trace elements such as Cd and As in the pathogenesis of CKDu.

AB - Chronic kidney disease of uncertain etiology (CKDu) in areas in and around Sri Lanka’s North Central Province has been identified as a major non-communicable disease due to its high prevalence and the burden on the public health system. Controversial evidence relating to the etiology and risk factors of CKDu has been reported. The most debated is the role of trace elements such as Cd and As in the pathogenesis of CKDu.

KW - Chronic kidney disease

KW - Sri Lanka

KW - Cadmium

KW - Arsenic

KW - Trace elements

KW - Minerals

U2 - 10.1016/j.jtemb.2019.04.019

DO - 10.1016/j.jtemb.2019.04.019

M3 - Article

C2 - 31109613

SN - 0946-672X

VL - 54

SP - 206

EP - 213

JO - Journal of Trace Elements in Medicine and Biology

JF - Journal of Trace Elements in Medicine and Biology

ER -

Systematic evaluation of exposure to trace elements and minerals in patients with chronic kidney disease of uncertain etiology (CKDu) in Sri Lanka

Abstract

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