The effect of automated preprocessing of RR interval tachogram on discrimination capability of Heart Rate Variability parameters

F. Marzbanrad, Herbert Jelinek, E. Ng, M. Tamayo, B. Hambly, C. McLachlan, S. Matthews, M. Palaniswami, A. Khandoker

Research output: Book chapter/Published conference paperConference paperpeer-review

5 Citations (Scopus)
38 Downloads (Pure)


Heart Rate Variability (HRV) has been extensively investigated for characterizing the autonomic nervous system (ANS) in controlling heart rate. Since ectopic beats, artefacts and noise of the ECG can affect the estimation of HRV features, pre-processing of the RR tachogram can improve the accuracy of HRV analysis and discriminatory power. This paper investigates the effect of different automated preprocessing methods on discriminatory capability of HRV analysis with an example of comparison between different groups of normal and type II diabetic patients with different Angiotensin-Converting Enzyme (ACE) gene polymorphism. Results show that smaller p-values and therefore higher discriminatory capability are found when preprocessing is used, while none of the features can show significant difference if they are estimated from the raw R-R sequence. Secondly, the preprocessing methods do not have the same effect for all HRV features.
Original languageEnglish
Title of host publicationComputing in Cardiology 2013
Subtitle of host publicationVolume 40
Place of PublicationUnited States
PublisherIEEE, Institute of Electrical and Electronics Engineers
Number of pages4
ISBN (Electronic)9781479908868
ISBN (Print)9781479908844
Publication statusPublished - 2013
Event40th Computing in Cardiology Conference, CinC 2013
- School of Engineering (Betancourt Building), The University of Zaragoza, Zaragoza, Spain
Duration: 22 Sept 201325 Sept 2013 (Conference proceedings) (Conference website)


Conference40th Computing in Cardiology Conference, CinC 2013
OtherComputing in Cardiology provides an international forum for scientists and professionals from the fields of medicine, physics, engineering and computer science, and has been held annually since 1974.
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