Abstract
Multi-scale measures have been used extensively to characterize non-linear dynamics of heart beats. However a physiological interpretation of the exponents associated with various scales of these measures and the role of the sympathetic and parasympathetic activities have not been attempted. In this study three multi-scale measures were compared at different scales in a pharmacological autonomic blockade experiment, starting with a control phase. It was then followed by injection of propranolol causing sympathetic blockade and injection of atropine resulting in the blockade of both sympathetic and parasympathetic pathways. Multiscale Entropy (MSE), Multi Fractal Detrended Fluctuation Analysis (MFDFA) and Renyi Entropy (RE) were compared using a paired test statistics. The measures performed differently depending on the scale factors and RE showed the best results indicating a good discrimination particularly at higher scale exponents. This study provides a basis for understanding the effect of autonomic activity on multi-scale measures with respect to changes in parasympathetic and sympathetic activity.
Original language | English |
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Title of host publication | EMBEC and NBC 2017 |
Subtitle of host publication | Joint conference of the European medical and biological engineering conference EMBEC 2017 and the Nordic-Baltic conference on biomedical engineering and medical physics |
Editors | Hannu Eskola, Outi Vaisanen, Jari Viik, Jari Hyttinen |
Publisher | Springer-Verlag London Ltd. |
Pages | 462-465 |
Number of pages | 4 |
Volume | 65 |
ISBN (Electronic) | 9789811051227 |
ISBN (Print) | 9789811051210 |
DOIs | |
Publication status | Published - 2018 |
Event | Joint Conference of European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC) - Tampere Hall, Tampere, Finland Duration: 11 Jun 2017 → 15 Jun 2017 https://web.archive.org/web/20180213061956/https://embec2017.org/ (Conference website) https://link.springer.com/book/10.1007/978-981-10-5122-7 (Conference proceedings) |
Publication series
Name | IFMBE Proceedings |
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Publisher | Springer Nature |
Volume | 65 |
ISSN (Print) | 1680-0737 |
ISSN (Electronic) | 1433-9277 |
Conference
Conference | Joint Conference of European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC) |
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Country/Territory | Finland |
City | Tampere |
Period | 11/06/17 → 15/06/17 |
Other | It is our pleasure to invite you to the joint conference of the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC), in Tampere, Finland, in June 2017. These two long running conferences are now combined for the first time with aim to build a truly cross-discipline conference. We aim to present all traditional BMES and BME areas, but also highlight new emerging fields, such as tissue engineering, bioinformatics, biosensing, neurotechnology, additive manufacturing technologies for medicine and biology, and bioimaging, to name a few. Moreover, we will emphasize the role of education, translational research, and commercialization.The scientific and social program at EMBEC’17 & NBC’17 provides an excellent platform for engineers, physicists, biologists, and clinical experts to enhance our knowledge and scientific achievements by bridging complementary disciplines and new findings into an interactive and attractive forum. |
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