Many individuals age and die without clinically defined diseases while some individuals develop certain age-related diseases in middle or old age. This suggests there is a transition period when the normal aging processes turn into pathology for age-related diseases such as neurodegenerative disease. We propose that the interactions between normal aging process and environmental factors can deviate normal aging processes into a precursor state that has tendance to develop into age-related pathologies. The micro environments such as epigenetic changes and macro environments such as pathogens external to the organisms can affect the fate of this precursor state. This precursor hypothesis can guide early detection and intervention on aging-diseases progression.
|Publication status||Published - 02 Sept 2021|
|Event||The 9th Aging Research & Drug Discovery Meeting : ARDD 2021 - Ceremonial Hall, University of Copenhagen and online, Copenhagen , Denmark|
Duration: 31 Aug 2021 → 03 Sept 2021
|Conference||The 9th Aging Research & Drug Discovery Meeting|
|Period||31/08/21 → 03/09/21|