Therapeutic potential of rice-derived polyphenols on obesity-related oxidative stress and inflammation

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Abstract

Global obesity rates are of epidemic proportion. With limited treatments available there is a large demand for therapeutic alternatives. Polyphenols derived from coloured rice varieties may serve as a potential functional food alternative in combating obesity and obesity-related diseases. The antioxidant and anti-inflammatory properties of polyphenols found in coloured rice varieties could have the ability to neutralize oxidative stress and modulate inflammatory responses in obese populations. This review discusses polyphenols derived from rice, the oxidative stress and inflammatory pathways involved in obesity pathogenesis, bioavailability of polyphenols and the therapeutic potential of polyphenols on transcriptional and molecular pathways related to obesity and obesity-related diseases.
Original languageEnglish
Pages (from-to)255-262
Number of pages8
JournalJournal of Applied Biomedicine
Volume16
Issue number4
Early online dateMar 2018
DOIs
Publication statusPublished - Nov 2018

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Oxidative stress
Polyphenols
polyphenols
Oxidative Stress
obesity
oxidative stress
Obesity
inflammation
Inflammation
rice
therapeutics
obesity-related diseases
Therapeutics
Functional Food
anti-inflammatory activity
functional foods
bioavailability
Anti-Inflammatory Agents
pathogenesis
Antioxidants

Cite this

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title = "Therapeutic potential of rice-derived polyphenols on obesity-related oxidative stress and inflammation",
abstract = "Global obesity rates are of epidemic proportion. With limited treatments available there is a large demand for therapeutic alternatives. Polyphenols derived from coloured rice varieties may serve as a potential functional food alternative in combating obesity and obesity-related diseases. The antioxidant and anti-inflammatory properties of polyphenols found in coloured rice varieties could have the ability to neutralize oxidative stress and modulate inflammatory responses in obese populations. This review discusses polyphenols derived from rice, the oxidative stress and inflammatory pathways involved in obesity pathogenesis, bioavailability of polyphenols and the therapeutic potential of polyphenols on transcriptional and molecular pathways related to obesity and obesity-related diseases.",
keywords = "Obesity, Polyphenol, Rice, Oxidative stress, Inflammation",
author = "Esther Callcott and Abishek Santhakumar and Jixun Luo and Christopher Blanchard",
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TY - JOUR

T1 - Therapeutic potential of rice-derived polyphenols on obesity-related oxidative stress and inflammation

AU - Callcott, Esther

AU - Santhakumar, Abishek

AU - Luo, Jixun

AU - Blanchard, Christopher

PY - 2018/11

Y1 - 2018/11

N2 - Global obesity rates are of epidemic proportion. With limited treatments available there is a large demand for therapeutic alternatives. Polyphenols derived from coloured rice varieties may serve as a potential functional food alternative in combating obesity and obesity-related diseases. The antioxidant and anti-inflammatory properties of polyphenols found in coloured rice varieties could have the ability to neutralize oxidative stress and modulate inflammatory responses in obese populations. This review discusses polyphenols derived from rice, the oxidative stress and inflammatory pathways involved in obesity pathogenesis, bioavailability of polyphenols and the therapeutic potential of polyphenols on transcriptional and molecular pathways related to obesity and obesity-related diseases.

AB - Global obesity rates are of epidemic proportion. With limited treatments available there is a large demand for therapeutic alternatives. Polyphenols derived from coloured rice varieties may serve as a potential functional food alternative in combating obesity and obesity-related diseases. The antioxidant and anti-inflammatory properties of polyphenols found in coloured rice varieties could have the ability to neutralize oxidative stress and modulate inflammatory responses in obese populations. This review discusses polyphenols derived from rice, the oxidative stress and inflammatory pathways involved in obesity pathogenesis, bioavailability of polyphenols and the therapeutic potential of polyphenols on transcriptional and molecular pathways related to obesity and obesity-related diseases.

KW - Obesity

KW - Polyphenol

KW - Rice

KW - Oxidative stress

KW - Inflammation

U2 - 10.1016/j.jab.2018.03.001

DO - 10.1016/j.jab.2018.03.001

M3 - Review article

VL - 16

SP - 255

EP - 262

JO - Journal of Applied Biomedicine

JF - Journal of Applied Biomedicine

SN - 1214-021X

IS - 4

ER -