Therapeutic potential of rice-derived polyphenols on obesity-related oxidative stress and inflammation

Esther Callcott; Abishek Santhakumar; Jixun Luo; Christopher Blanchard

doi:10.1016/j.jab.2018.03.001

Therapeutic potential of rice-derived polyphenols on obesity-related oxidative stress and inflammation

Esther Callcott, Abishek Santhakumar, Jixun Luo, Christopher Blanchard

Research output: Contribution to journal › Review article › peer-review

11 Citations (Scopus)

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Abstract

Global obesity rates are of epidemic proportion. With limited treatments available there is a large demand for therapeutic alternatives. Polyphenols derived from coloured rice varieties may serve as a potential functional food alternative in combating obesity and obesity-related diseases. The antioxidant and anti-inflammatory properties of polyphenols found in coloured rice varieties could have the ability to neutralize oxidative stress and modulate inflammatory responses in obese populations. This review discusses polyphenols derived from rice, the oxidative stress and inflammatory pathways involved in obesity pathogenesis, bioavailability of polyphenols and the therapeutic potential of polyphenols on transcriptional and molecular pathways related to obesity and obesity-related diseases.

Original language	English
Pages (from-to)	255-262
Number of pages	8
Journal	Journal of Applied Biomedicine
Volume	16
Issue number	4
Early online date	Mar 2018
DOIs	https://doi.org/10.1016/j.jab.2018.03.001
Publication status	Published - Nov 2018

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10.1016/j.jab.2018.03.001

21106218 published articleFinal published version, 1.02 MBLicence: CC BY-NC-ND

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title = "Therapeutic potential of rice-derived polyphenols on obesity-related oxidative stress and inflammation",

abstract = "Global obesity rates are of epidemic proportion. With limited treatments available there is a large demand for therapeutic alternatives. Polyphenols derived from coloured rice varieties may serve as a potential functional food alternative in combating obesity and obesity-related diseases. The antioxidant and anti-inflammatory properties of polyphenols found in coloured rice varieties could have the ability to neutralize oxidative stress and modulate inflammatory responses in obese populations. This review discusses polyphenols derived from rice, the oxidative stress and inflammatory pathways involved in obesity pathogenesis, bioavailability of polyphenols and the therapeutic potential of polyphenols on transcriptional and molecular pathways related to obesity and obesity-related diseases.",

keywords = "Obesity, Polyphenol, Rice, Oxidative stress, Inflammation",

author = "Esther Callcott and Abishek Santhakumar and Jixun Luo and Christopher Blanchard",

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T1 - Therapeutic potential of rice-derived polyphenols on obesity-related oxidative stress and inflammation

AU - Callcott, Esther

AU - Santhakumar, Abishek

AU - Luo, Jixun

AU - Blanchard, Christopher

PY - 2018/11

Y1 - 2018/11

N2 - Global obesity rates are of epidemic proportion. With limited treatments available there is a large demand for therapeutic alternatives. Polyphenols derived from coloured rice varieties may serve as a potential functional food alternative in combating obesity and obesity-related diseases. The antioxidant and anti-inflammatory properties of polyphenols found in coloured rice varieties could have the ability to neutralize oxidative stress and modulate inflammatory responses in obese populations. This review discusses polyphenols derived from rice, the oxidative stress and inflammatory pathways involved in obesity pathogenesis, bioavailability of polyphenols and the therapeutic potential of polyphenols on transcriptional and molecular pathways related to obesity and obesity-related diseases.

AB - Global obesity rates are of epidemic proportion. With limited treatments available there is a large demand for therapeutic alternatives. Polyphenols derived from coloured rice varieties may serve as a potential functional food alternative in combating obesity and obesity-related diseases. The antioxidant and anti-inflammatory properties of polyphenols found in coloured rice varieties could have the ability to neutralize oxidative stress and modulate inflammatory responses in obese populations. This review discusses polyphenols derived from rice, the oxidative stress and inflammatory pathways involved in obesity pathogenesis, bioavailability of polyphenols and the therapeutic potential of polyphenols on transcriptional and molecular pathways related to obesity and obesity-related diseases.

KW - Obesity

KW - Polyphenol

KW - Rice

KW - Oxidative stress

KW - Inflammation

U2 - 10.1016/j.jab.2018.03.001

DO - 10.1016/j.jab.2018.03.001

M3 - Review article

VL - 16

SP - 255

EP - 262

JO - Journal of Applied Biomedicine

JF - Journal of Applied Biomedicine

SN - 1214-021X

IS - 4

ER -