Validation of the BrockTB Stat-Pak assay for detection of tuberculosis in Eurasian badgers (Meles meles) and influence of disease severity on diagnostic accuracy

Mark A. Chambers, Tim Crawshaw, Sue Waterhouse, Richard Delahay, R. Glyn Hewinson, Konstantin P. Lyashchenko

    Research output: Contribution to journalArticlepeer-review

    58 Citations (Scopus)

    Abstract

    A lateral-flow immunoassay (BrockTB Stat-Pak) for detecting tuberculosis in Eurasian badgers was 49% sensitive and 93% specific against culture for M. bovis (n = 1,464) at necropsy. However, the sensitivity was significantly higher (66 to 78%) in animals with more severe tuberculosis, indicating that the BrockTB Stat-Pak may be useful for the detection of badgers with the greatest risk of transmitting disease.

    Original languageEnglish
    Pages (from-to)1498-1500
    Number of pages3
    JournalJournal of Clinical Microbiology
    Volume46
    Issue number4
    DOIs
    Publication statusPublished - 01 Apr 2008

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