The One Health concept has been extensively used to describe those practices that support transdisciplinary collaborations involving animal and human health and the environment. During the past International Society of Veterinary Epidemiology and Economics (ISVEE) conference in Merida (Mexico) in November 2015, a panel discussion was held to identify gaps and needs required for success with such approaches. Key messages included further development of dynamic, trans disciplinary collaborations, new mechanisms for obtaining, integrating and interpreting data from diverse sources, the identification of One Health joint priorities and resources for the veterinary and public health professions, and operationalization and institutionalization of One Health. Additionally, all abstracts that were presented at ISVEE containing the term 'One Health' were identified. There has been an increase in the use of the term over time. One Health research has been presented at ISVEE since at least as early as 2009 and has been highlighted at the conference for work carried out in at least 41 countries from 69 research centers or institutions, with highly diversified articles, which reveals the richness of this field of research.