Vitex agnus-castus for the treatment of cyclic mastalgia: A systematic review and meta-analysis

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Abstract

Cyclic mastalgia (CM) is premenstrual bilateral and diffuse breast pain that presents cyclically and affects women in their reproductive years. It may associate with latent hyperprolactinemia due to the insufficient inhibitory effect of dopamine on the pituitary gland. Vitex agnus-castus (VAC) is known for its dopaminergic activity and its possible actions on CM and latent hyperprolactinemia. However, the treatment effect of VAC on CM remains unclear.
Original languageEnglish
Pages (from-to)262-278
Number of pages17
JournalJournal of Women's Health
Volume29
Issue number2
Early online date07 Feb 2020
DOIs
Publication statusPublished - 07 Feb 2020

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