Vitex agnus-castus for the treatment of cyclic mastalgia: A systematic review and meta-analysis

Soo Liang Ooi; Stephanie Watts; Rhett McClean; Sokcheon Pak

doi:10.1089/jwh.2019.7770

Vitex agnus-castus for the treatment of cyclic mastalgia: A systematic review and meta-analysis

Soo Liang Ooi, Stephanie Watts, Rhett McClean, Sokcheon Pak

Biomedical Sciences

Research output: Contribution to journal › Review article › peer-review

1 Citation (Scopus)

Abstract

Cyclic mastalgia (CM) is premenstrual bilateral and diffuse breast pain that presents cyclically and affects women in their reproductive years. It may associate with latent hyperprolactinemia due to the insufficient inhibitory effect of dopamine on the pituitary gland. Vitex agnus-castus (VAC) is known for its dopaminergic activity and its possible actions on CM and latent hyperprolactinemia. However, the treatment effect of VAC on CM remains unclear.

Original language	English
Pages (from-to)	262-278
Number of pages	17
Journal	Journal of Women's Health
Volume	29
Issue number	2
Early online date	07 Feb 2020
DOIs	https://doi.org/10.1089/jwh.2019.7770
Publication status	Published - 07 Feb 2020

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10.1089/jwh.2019.7770

https://www.ncbi.nlm.nih.gov/pubmed/31464546

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title = "Vitex agnus-castus for the treatment of cyclic mastalgia: A systematic review and meta-analysis",

abstract = "Cyclic mastalgia (CM) is premenstrual bilateral and diffuse breast pain that presents cyclically and affects women in their reproductive years. It may associate with latent hyperprolactinemia due to the insufficient inhibitory effect of dopamine on the pituitary gland. Vitex agnus-castus (VAC) is known for its dopaminergic activity and its possible actions on CM and latent hyperprolactinemia. However, the treatment effect of VAC on CM remains unclear.",

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AU - McClean, Rhett

AU - Pak, Sokcheon

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N2 - Cyclic mastalgia (CM) is premenstrual bilateral and diffuse breast pain that presents cyclically and affects women in their reproductive years. It may associate with latent hyperprolactinemia due to the insufficient inhibitory effect of dopamine on the pituitary gland. Vitex agnus-castus (VAC) is known for its dopaminergic activity and its possible actions on CM and latent hyperprolactinemia. However, the treatment effect of VAC on CM remains unclear.

AB - Cyclic mastalgia (CM) is premenstrual bilateral and diffuse breast pain that presents cyclically and affects women in their reproductive years. It may associate with latent hyperprolactinemia due to the insufficient inhibitory effect of dopamine on the pituitary gland. Vitex agnus-castus (VAC) is known for its dopaminergic activity and its possible actions on CM and latent hyperprolactinemia. However, the treatment effect of VAC on CM remains unclear.

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DO - 10.1089/jwh.2019.7770

M3 - Review article

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