The economic value of wine has increased over the years due to the emergence of new producers and new markets. In line with this, the global distribution of research outputs in viticulture and oenology has also shifted since this informs wine production and consumption. This study investigates the trends in wine and grape publications indexed in Web of Science (2002–2017). Methods and Results: Using bibliometric techniques, citation impact, research specialisation and collaboration network were analysed. China had the largest annual growth in wine-related publications, Spain had the largest total number of wine-related publications and the USA had the highest citation impact. Australia was the sixth in terms of publication share and fifth in terms of citation share. European countries collaborate mostly with one another and Portuguese and Spanish speaking countries form another collaboration cluster. Wine and grape science is a diverse field with food science and technology scholars being the main contributors and funding coming mostly from governments agencies. Conclusions: Scientific collaboration in the field does not closely follow the grouping of countries into Old and New World wine producers. While the amount of published wine research was strongly correlated with wine production for Old World countries, there was no correlation for New World countries. Significance of the Study: This study improves the search strategy for retrieving wine and grape research from scholarly databases. It also provides an up-to-date account of global wine research trends.